Introduction:

NGS Sample Preparation Market was valued at US$ 4.9 billion in 2024 and is projected to grow at a CAGR of 7.5 % to reach US$ 9.5 billion by 2034.

The concept of NGS technology is analogous to Sanger’s sequencing- DNA polymerases catalyze to the incorporation of fluorescently labelled deoxyribonucleotide triphosphates (dNTPs) into the templets of DNA during the sequential cycles of DNA synthesis. In every cycle, the nucleotides are recognized by fluorophore excitation when it is incorporated. The main difference is that, instead of sequencing a single DNA fragment, NGS sequences the millions of fragments side by side. The process of analyzing the entire DNA sequence of an organism’s genome at a single time. Any biological sample containing a full copy of the DNA for the full sequencing, such as saliva, epithelial cells or bone marrow. It allows doctors to test many genes of a cancer at single time. NSG can be performed on genetic material of patient which has been surgically removed. DNA NGS involves DNA fragmentation, library preparation, massive parallel sequencing, bioinformatics analysis, and variant/mutation annotation and interpretation.

Disclaimer: This data is only a representation. Actual data may vary and will be available in the report.

The increase in the prevalence of genetic disorders increases the NGS sample preparation which is the major factor for the growth of the market. Additionally, for the genetic testing increasing due to direct contact with the consumer is another fueling factor for the growth of the target market. Moreover, increasing the prevalence of infectious diseases rise the demand for NGS sample preparation which is the propelling factor for the growth of the market. Also, in the field of genomics the research funding increases which is the boosting factor for the market growth.

However, the high cost of the instruments for automated NGS sample preparation is the main restraining factor for the growth of the target market. Besides this, the lack of advanced genetic testing centers hampers the growth of the market. Nevertheless, the adoption of automated NGS sample preparation in the emerging market can create an opportunity in the market over the forecast period.

The NGS sample preparation market is segmented based on product, workflow, therapy area, application, and region.

Based on the product, the NGS sample preparation market is segmented into the workstation (open system and closed system), standalone, and consumables. Based on the workflow, the target market is segmented into manual NGS sample preparation fragmentation and quality control. Based on the therapy area, the market is classified into oncology and neonatal. Based on the application, the target market is bifurcated into DNA sequencing and metagenomics.

Regional Insights:

Disclaimer: This data is only a representation. Actual data may vary and will be available in the report.

On region the NGS sample preparation market is segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. The market in North America accounts highest revenue share to the NGS sample preparation market due to the growing demand for advanced medical technologies in genomics. Europe region is anticipated for significant growth for the market over the forecast period.

Report Scope:

Attribute	Details
Market Size 2024	US$ 4.9 billion
Projected Market Size 2034	US$ 9.5 billion
CAGR Growth Rate	7.5%
Base year for estimation	2023
Forecast period	2024 – 2034
Market representation	Revenue in USD Billion & CAGR from 2024 to 2034
Market Segmentation	By Product- Workstation (Open System and Closed System), Standalone, and Consumables By Workflow– Fragmentation, and Quality Control By Therapy Area- Oncology, and Neonatal By Application– DNA Sequencing, and Metagenomics
Regional scope	North America - U.S., Canada Europe - UK, Germany, Spain, France, Italy, Russia, Rest of Europe Asia Pacific - Japan, India, China, South Korea, Australia, Rest of Asia-Pacific Latin America - Brazil, Mexico, Argentina, Rest of Latin America Middle East & Africa - South Africa, Saudi Arabia, UAE, Rest of Middle East & Africa
Report coverage	Revenue forecast, company share, competitive landscape, growth factors, and trends

Segments Covered in the Report:

This report forecasts revenue growth at , regional, and country levels and provides an analysis of the latest industry trends and opportunities in each of the sub-segments from 2024 to 2034. For the purpose of this study, has segmented the NGS Sample Preparation Market report based on Product, Workflow, Therapy Area, Application and region:

NGS Sample Preparation Market, By Region:

• North America
  • Middle East & Africa
    • • GCC
      • Israel
      • South Africa
      • Rest of Middle East & Africa
  • Latin America
    • • Brazil
      • Mexico
      • Rest of Latin America
  • Asia Pacific
    • • China
      • India
      • Japan
      • South Korea
      • Rest of Asia Pacific
  • Europe
    • • Germany
      • UK
      • France
      • Russia
      • Italy
      • Rest of Europe
  • • U.S.
    • Canada

The key players operating the NGS sample preparation market involves Agilent Technologies, Aurora Biomed Inc., Bio-Rad Laboratories, Inc., Danaher Corporation, Eppendorf AG, F. Hoffmann-La Roche AG, Hamilton Company, Illumina, Inc., New England Biolabs, Inc., and Oxford Nanopore Technologies Limited. Prominent players operating in the target market are focusing on strategic partnerships as well as the launching of the products to gain a competitive edge in the target market. For instance, in 2017, Bio-Rad Laboratories, Inc. signed the bond of partnership with the Illumina to introduce the Bio-Rad's single-cell sequencing solution.

Recent Development:

• In February 2024, the first electrowetting-based sample preparation technology for next-generation sequencing has been released by lab automation firm Volta Labs. The device, called Callisto, is intended to provide several workflows for both short- and long-read sequencing. Callisto is a benchtop device that can process up to 24 samples at once during a single operation, such library preparation and DNA extraction. The device has the capacity to load four samples in batches at once, each of which has a separate electrowetting surface module. In particular, the platform works with cell line, buffy coat, and blood samples for DNA extraction. Volta Laboratories presently offers a kit for enzymatic fragmentation-based DNA library preparation for short-read sequencing in addition to the Pacific Biosciences SMRTbell prep kit 3.0.
• In September 2023, to aid in resolving the typical problems that researchers have when getting ready to run NGS samples, MIRO CANVAS was created. NGS operations are significantly simplified by this ground-breaking tool, which enables increased walk-away time through completely automated target enrichment hybridization and library preparation. The techniques that have been verified encompass both short-read applications, including target enrichment and whole genome sequencing (WGS), and long-read applications, like PacBio sequencing. Accuracy, precision, and dependability are guaranteed for excellent outcomes with these preloaded processes.

• Agilent Technologies*
  • Company Overview
  • Product Portfolio
  • Key Highlights
  • Financial Performance
  • Business Strategies
• Aurora Biomed Inc.
• Bio-Rad Laboratories, Inc.
• Danaher Corporation
• Eppendorf AG
• F. Hoffmann-La Roche AG
• Hamilton Company
• Illumina, Inc.
• New England Biolabs, Inc.
• Oxford Nanopore Technologies Limited.

“*” marked represents similar segmentation in other categories in the respective section.

1. Research Objective and Assumption
   • Preface
   • Research Objectives
   • Study Scope
   • Years considered for the study
   • Assumptions
   • Abbreviations
2. Research Methodology
   • Research data
   • Primary Data
     • Primary Interviews
     • Primary Breakdown
     • Key data from Primary Sources
     • Key Industry Insights
   • Secondary Data
     • Major Secondary Sources
     • Secondary Sources
   • Market Estimation
   • Top-Down Approach
     • Approach for estimating Market Share by Top-Down Analysis (Supply Side)
   • Bottom-Up Approach
     • Approach for estimating market share by Bottom-up Analysis (Demand Side)
   • Market Breakdown and Data Triangulation
   • Research Assumptions
3. Market Preview
   • Executive Summary
   • Key Findings—Global Outlook for NGS Sample Preparation Strategies
     • Key Questions this Study will Answer
     • Market Snippet, By Products
     • Market Snippet, By Workflow
     • Market Snippet, By Therapy Area
     • Market Snippet, By Application
     • Market Snippet, By Region
   • Opportunity Map Analysis
   • Executive Summary—3 Big Predictions
4. Market Dynamics, Regulations, and Trends Analysis
   • Market Dynamics
     • Drivers
     • Restraints
     • Market Opportunities
     • Market Trends
   • DR Impact Analysis
   • PEST Analysis
   • Porter’s Five Forces Analysis
   • Opportunity Orbit
   • Market Investment Feasibility Index
   • Macroeconomic Factor Analysis
5. Market Segmentation, By Products, 2020 – 2030, (US$ Mn)
   • Overview
     • Market Value and Forecast (US$ Mn), and Share Analysis (%), 2020 – 2030
     • Y-o-Y Growth Analysis (%), 2020 – 2030
     • Segment Trends
   • Workstation
     • Overview
     • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2030

• Open System
  • • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2030

• Closed System
  • • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2030
  • Standalone
    • Overview
    • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2030
  • Consumable
    • Overview
    • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2030

1. Market Segmentation, By Workflow, 2020 – 2030, (US$ Mn)
   • Overview
     • Market Value and Forecast (US$ Mn), and Share Analysis (%), 2020 – 2030
     • Y-o-Y Growth Analysis (%), 2020 – 2030
     • Segment Trends
   • Fragmentation
     • Overview
     • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2030
   • Quality Control
     • Overview
     • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2030
2. Market Segmentation, By Therapy Area, 2020 – 2030, (US$ Mn)
   • Overview
     • Market Value and Forecast (US$ Mn), and Share Analysis (%), 2020 – 2030
     • Y-o-Y Growth Analysis (%), 2020 – 2030
     • Segment Trends
   • Oncology
     • Overview
     • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2030
   • Neonatal
     • Overview
     • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2030
3. Market Segmentation, By Application, 2020 – 2030, (US$ Mn)
   • Overview
     • Market Value and Forecast (US$ Mn), and Share Analysis (%), 2020 – 2030
     • Y-o-Y Growth Analysis (%), 2020 – 2030
     • Segment Trends
   • DNA Sequencing
     • Overview
     • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2030
   • Metagenomics
     • Overview
     • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2030
4. Global Market, By Region, 2020 – 2030, (US$ Mn)
   • Overview
     • Market Value and Forecast (US$ Mn), and Share Analysis (%), 2020 – 2030
     • Y-o-Y Growth Analysis (%), 2020 – 2030
     • Regional Trends
   • North America
     • Market Size and Forecast (US$ Mn), By Products, 2020 – 2030
     • Market Size and Forecast (US$ Mn), By Workflow, 2020 – 2030
     • Market Size and Forecast (US$ Mn), By Therapy Area, 2020 – 2030
     • Market Size and Forecast (US$ Mn), By Application, 2020 – 2030
     • Market Size and Forecast (US$ Mn), By Country, 2020 – 2030
       • U.S.
       • Canada
   • Europe
     • Market Size and Forecast (US$ Mn), By Products, 2020 – 2030
     • Market Size and Forecast (US$ Mn), By Workflow, 2020 – 2030
     • Market Size and Forecast (US$ Mn), By Therapy Area, 2020 – 2030
     • Market Size and Forecast (US$ Mn), By Application, 2020 – 2030
     • Market Size and Forecast (US$ Mn), By Country, 2020 – 2030
       • Germany
       • UK
       • France
       • Russia
       • Italy
       • Rest of Europe
   • Asia Pacific
     • Market Size and Forecast (US$ Mn), By Products, 2020 – 2030
     • Market Size and Forecast (US$ Mn), By Workflow, 2020 – 2030
     • Market Size and Forecast (US$ Mn), By Therapy Area, 2020 – 2030
     • Market Size and Forecast (US$ Mn), By Application, 2020 – 2030
     • Market Size and Forecast (US$ Mn), By Country, 2020 – 2030
       • China
       • India
       • Japan
       • South Korea
       • Rest of Asia Pacific
   • Latin America
     • Market Size and Forecast (US$ Mn), By Products, 2020 – 2030
     • Market Size and Forecast (US$ Mn), By Workflow, 2020 – 2030
     • Market Size and Forecast (US$ Mn), By Therapy Area, 2020 – 2030
     • Market Size and Forecast (US$ Mn), By Application, 2020 – 2030
     • Market Size and Forecast (US$ Mn), By Country, 2020 – 2030
       • Brazil
       • Mexico
       • Rest of Latin America
   • Middle East & Africa
     • Market Size and Forecast (US$ Mn), By Products, 2020 – 2030
     • Market Size and Forecast (US$ Mn), By Workflow, 2020 – 2030
     • Market Size and Forecast (US$ Mn), By Therapy Area, 2020 – 2030
     • Market Size and Forecast (US$ Mn), By Application, 2020 – 2030
     • Market Size and Forecast (US$ Mn), By Country, 2020 – 2030
       • GCC
       • Israel
       • South Africa
       • Rest of Middle East
5. Competitive Landscape
   • Heat Map Analysis
   • Market Presence and Specificity Analysis
6. Company Profiles
   • Agilent Technologies
     • Company Overview
     • Product Portfolio
     • Key Highlights
     • Financial Performance
   • B. Braun Melsungen AG
   • Aurora Biomed Inc.
   • Bio-Rad Laboratories, Inc.
   • Danaher Corporation
   • Eppendorf AG
   • F. Hoffmann-La Roche AG,
   • Hamilton Company
   • Illumina, Inc.
   • New England Biolabs, Inc.
   • Oxford Nanopore Technologies Limited
7. The Last Word
   • Future Impact
   • About Us
   • Contact