Oligonucleotide Synthesis Market, By Product & Service (Synthesizer, Custom Oligonucleotide Synthesis, Probes, Premiers, Linkers & Adaptors and Reagents & Consumables), By End-User (Pharmaceutical & Biotechnology Companies, Academic Research Institutes, Diagnostic Laboratories and Others), By Application (Research, Therapeutics and Diagnostics), and By Region (North America, Europe, Asia Pacific, Latin America, and Middle East & Africa) - Trends, Analysis and Forecast till 2030

Report Code: PMI377719 | Publish Date: March 2024 | No. of Pages: 165

Global Oligonucleotide Synthesis Market By Overview

Introduction:

Oligonucleotide Synthesis Market accounted for US$ 5.17 billion in 2020 and is estimated to be US$ 12.09 billion by 2030 and is anticipated to register a CAGR of 9.0%.

Enzymatic chemistry and genetic engineering produce oligonucleotides, which are little fragments of nucleic acids. Oligonucleotides are mostly used in research laboratories for diagnostic, educational, and industrial purposes, as well as medicinal purposes. Oligonucleotide synthesis can be done professionally to serve a large number of customers, or it can be done independently using DNA synthesizers. Improvements in oligonucleotide synthesis, amplification, and computerization have completely altered biological research in recent years. It is also possible to make adjustments and obtain the required cycle quickly and easily online. The cost per base pair, error rates, durations, and throughput, among other factors, all affect the cost of these vital services.

Impact of Covid-19 pandemic on market

New generations of oligonucleotide medications, including mRNA and DNA vaccines, are currently being developed in response to the rising number of cases of coronavirus illness (COVID-19) and the need for a viable cure. Apart from that, the rising prevalence of cancer and other chronic illnesses has increased the demand for novel diagnostics, impacting the need for oligonucleotide synthesis to aid in the development of effective medicines and diagnostic tools. The industry is also being boosted by the growing elderly population and need for tailored treatments.

Global Oligonucleotide Synthesis Market By Dynamics

                                              

Decrease in cost of DNA sequencing drives the market

Over the last few years, advances in genomics research have resulted in a significant reduction in the cost of genome sequencing. NGS technology has drastically decreased the cost and enhanced the speed of DNA sequencing. The cost of sequencing a human genome has reduced significantly, according to statistics from the National Human Genome Research Institute (NHGRI), from around $5 million in 2008 to around $1,000 in 2017. Sequencing is increasingly being employed in genomics research to comprehend the various nature of reproductive medicine, oncology, and infectious illnesses, in addition to assembling genomes and investigating the genetic basis of human disorders.

Increasing government support and investment

Governments in a number of nations have made major investments in programmes connected to synthetic biology and genomics in recent years. These government investments have aided the development of new technology significantly. Oligonucleotides are an important aspect of these technologies, and increased investment and development in these domains will fuel oligonucleotide market growth. For instance, The Department of Biotechnology (DBT) launched the "Genome India Project" in January 2020. (GIP). The goal of the initiative is to collect 10,000 genetic samples from Indian residents in order to create a reference genome. Precision health, rare genetic disorders, the mutation spectrum of genetic and complex diseases in the Indian population, genetic epidemiology of multifactorial lifestyle diseases, and translational research are some of the project major areas.

Global Oligonucleotide Synthesis Market By Segmentation

The Oligonucleotide Synthesis Market report segments the market on the basis of product and service, application, end-user and region.

On the basis of Product and Service, the Oligonucleotide Synthesis Market is segmented into Synthesizer, Custom Oligonucleotide Synthesis, Probes, Premiers, Linkers & Adaptors and Reagents & Consumables. On the basis of Application, the target market is segmented into Research, Therapeutics and Diagnostics. Based on End-User, the market is segmented into Pharmaceutical & Biotechnology Companies, Academic Research Institutes, Diagnostic Laboratories and Others.

Regional Insights:

Oligonucleotide Synthesis Market accounted for US$ 5.17 billion in 2020 and is estimated to be US$ 12.09 billion by 2030 and is anticipated to register a CAGR of 9.0%. On region the Oligonucleotide Synthesis Market is segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. The oligonucleotide synthesis market is expected to be dominated by North America in 2020, followed by Europe. During the projection period, however, demand from the Asia-Pacific region is predicted to expand at the quickest CAGR. Some of the primary reasons supporting the growth of the oligonucleotides market in the APAC region include increasing availability of synthesized oligonucleotides, strong presence of pharma and biotech businesses, expanding research outsourcing to CROs, and increased R&D funding and activities. For many stakeholders in the oligonucleotide synthesis business, developed countries such as the United States and European nations have been major marketplaces.

Report Scope:

Attribute

Details

Base year for estimation

2020

Forecast period

2020 – 2029

Market representation

Revenue in USD Million & CAGR from 2020 – 2029

Market Segmentation

By Product & Services - Synthesizer, Custom Oligonucleotide Synthesis, Probes, Premiers, Linkers & Adaptors and Reagents & Consumables

By End-User – Pharmaceutical & Biotechnology Companies, Academic Research Institutes, Diagnostic Laboratories and Others

By Application – Research, Therapeutics and Diagnostics

Regional scope

North America - U.S., Canada

Europe - UK, Germany, Spain, France, Italy, Russia, Rest of Europe

Asia Pacific - Japan, India, China, South Korea, Australia, Rest of Asia-Pacific

Latin America - Brazil, Mexico, Argentina, Rest of Latin America

Middle East & Africa - South Africa, Saudi Arabia, UAE, Rest of Middle East & Africa

Report coverage

Revenue forecast, company share, competitive landscape, growth factors, and trends

Segments Covered in the Report:

This report forecasts revenue growth at , regional, and country levels and provides an analysis of the latest industry trends and opportunities in each of the sub-segments from 2019 to 2029. For the purpose of this study, has segmented the Oligonucleotide Synthesis Market report based on product & service, application, end-user and Region.

segmentation - Oligonucleotide Synthesis Market

Oligonucleotide Synthesis Market, By Region:

  • North America
    • Middle East & Africa
        • GCC
        • Israel
        • South Africa
        • Rest of Middle East & Africa
    • Latin America
        • Brazil
        • Mexico
        • Rest of Latin America
    • Asia Pacific
        • China
        • India
        • Japan
        • South Korea
        • Rest of Asia Pacific
    • Europe
        • Germany
        • UK
        • France
        • Russia
        • Italy
        • Rest of Europe
    • U.S.
    • Canada

Global Oligonucleotide Synthesis Market By Key Players

The key players operating in the Oligonucleotide Synthesis Market includes Integrated DNA Technologies, Inc. (U.S.) (Part of Danaher Corporation), Merck KGaA (Germany), Eurofins Scientific SE (Luxembourg), Thermo Fisher Scientific Inc. (U.S.), Agilent Technologies, Inc. (U.S.), GE Healthcare (U.S.), GeneDesign, Inc. (Japan) (Part of Ajinomoto Co.,Inc.), Kaneka Eurogentec (Belgium) (Part of Kaneka Corporation), LGC Biosearch Technologies (U.S.), Bio-synthesis Inc. (U.S.), TriLink BioTechnologies, LLC (U.S.) (Part of Maravai LifeSciences), and ATDBio Ltd. (U.K.) among others.

Thermo Fisher Scientific Inc.

Thermo Fisher Scientific is a scientific instrumentation, reagents and consumables, and software Services Company based in the United States. Oligo (dT)18 Primer from Thermo Scientific is a single-stranded 18-mer oligonucleotide with 5' and 3' hydroxyl ends. The primer comes as a 20X concentrated aqueous solution that is ready to use. The most cost-effective and quickest option to order oligonucleotides from us is through Value Oligos. Simply enter your sequence and then proceed to the checkout page. Value Oligos come in 25 nmol and 50 nmol sizes, with several purifying techniques.

Global Oligonucleotide Synthesis Market By Key Issues Addressed

Recent Highlights:

  • Microsynth AG (Switzerland) provided key reagents such as primer-probe sets to PCR testing labs in April 2020 to help molecular diagnostic companies develop and validate accurate, cutting-edge detection methods, as well as to provide comprehensive genomics expertise to research labs studying coronaviruses. The main contribution involves, among other things, the supply of SARS-CoV-2 detection RT-qPCR primer-probe sets and the synthesis of primers for NGS-based SARS-CoV-2 high-throughput diagnostic.
  • Bio-Synthesis Inc. (US) released ready-to-use cocktail mixes for COVID-19 study in June 2020, including the SARS-CoV-2 N1 Oligo Mix, the SARS-CoV-2 N2 Oligo Mix, and the Human RNase P (RP) Oligo Mix.

Global Oligonucleotide Synthesis Market By Company Profile

  • Integrated DNA Technologies, Inc.
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • Merck KGaA
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • Eurofins Scientific SE
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • Thermo Fisher Scientific Inc.
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • Agilent Technologies, Inc.
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • GE Healthcare
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • GeneDesign, Inc.
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • Kaneka Eurogentec
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • LGC Biosearch Technologies
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • Bio-synthesis Inc.
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies

Global Oligonucleotide Synthesis Market By Table of Contents

  1. Research Objective and Assumption
    • Preface
    • Research Objectives
    • Study Scope
    • Years considered for the study
    • Assumptions
    • Abbreviations
  2. Research Methodology
    •  Research data
    • Primary Data
      • Primary Interviews
      • Primary Breakdown
      • Key data from Primary Types
      • Key Industry Insights
    • Secondary Data
      • Major Secondary Types
      • Secondary Types
    • Market Estimation
    • Top-Down Approach
      • Approach for estimating Market Share by Top-Down Analysis (Supply Side)
    • Bottom-Up Approach
      • Approach for estimating market share by Bottom-up Analysis (Demand Side)
    • Market Breakdown and Data Triangulation
    • Research Assumptions
  3. Market Preview
    • Executive Summary
    • Key Findings—Global Outlook for Oligonucleotide synthesis  Strategies
      • Key Questions this Study will Answer
      • Market Snippet, By Product Type
      • Market Snippet, By Type
      • Market Snippet, By Application
      • Market Snippet, By Region
    • Opportunity Map Analysis
    • Executive Summary—3 Big Predictions
  4. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
      • Market Trends
    • DR Impact Analysis
    • PEST Analysis
    • Porter’s Five Forces Analysis
    • Opportunity Orbit
    • Market Investment Feasibility Index
    • Macroeconomic Factor Analysis
  5. Market Segmentation, By Product Type, 2020 – 2030, (US$ Mn)
    • Overview
      • Market Value and Forecast (US$ Mn), and Share Analysis (%), 2020 – 2030
      • Y-o-Y Growth Analysis (%), 2020 – 2030
      • Segment Trends
    • Synthesized Oligonucleotide Product
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2030
    • Reagents and Equipment
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2030
  6. Market Segmentation, By Type, 2020 – 2030, (US$ Mn)
    • Overview
      • Market Value and Forecast (US$ Mn), and Share Analysis (%), 2020 – 2030
      • Y-o-Y Growth Analysis (%), 2020 – 2030
      • Segment Trends
    • Custom Oligos
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2030
    • Predesigned Oligos
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2030
  7. Market Segmentation, By Type, 2020 – 2030, (US$ Mn)
    • Overview
      • Market Value and Forecast (US$ Mn), and Share Analysis (%), 2020 – 2030
      • Y-o-Y Growth Analysis (%), 2020 – 2030
      • Segment Trends
    • Research
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2030
    • Diagnostics
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2030
    • Therapeutics
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2030
  8. Global Market, By Region, 2020 – 2030, (US$ Mn)
    • Overview
      • Market Value and Forecast (US$ Mn), and Share Analysis (%), 2020 – 2030
      • Y-o-Y Growth Analysis (%), 2020 – 2030
      • Regional Trends
    • North America
      • Market Size and Forecast (US$ Mn), By Product Type, 2020 – 2030
      • Market Size and Forecast (US$ Mn), By Type, 2020 – 2030
      • Market Size and Forecast (US$ Mn), By Application, 2020 – 2030
      • Market Size and Forecast (US$ Mn), By Country, 2020 – 2030
        • U.S.
        • Canada
    • Europe
      • Market Size and Forecast (US$ Mn), By Product Type, 2020 – 2030
      • Market Size and Forecast (US$ Mn), By Type, 2020 – 2030
      • Market Size and Forecast (US$ Mn), By Application, 2020 – 2030
      • Market Size and Forecast (US$ Mn), By Country, 2020 – 2030
        • Germany
        • UK
        • France
        • Russia
        • Italy
        • Rest of Europe
    • Asia Pacific
      • Market Size and Forecast (US$ Mn), By Product Type, 2020 – 2030
      • Market Size and Forecast (US$ Mn), By Type, 2020 – 2030
      • Market Size and Forecast (US$ Mn), By Application, 2020 – 2030
      • Market Size and Forecast (US$ Mn), By Country, 2020 – 2030
        • China
        • India
        • Japan
        • South Korea
        • Rest of Asia Pacific
    • Latin America
      • Market Size and Forecast (US$ Mn), By Product Type, 2020 – 2030
      • Market Size and Forecast (US$ Mn), By Type, 2020 – 2030
      • Market Size and Forecast (US$ Mn), By Application, 2020 – 2030
      • Market Size and Forecast (US$ Mn), By Country, 2020 – 2030
        • Brazil
        • Mexico
        • Rest of Latin America
    • Middle East & Africa
      • Market Size and Forecast (US$ Mn), By Product Type, 2020 – 2030
      • Market Size and Forecast (US$ Mn), By Type, 2020 – 2030
      • Market Size and Forecast (US$ Mn), By Application, 2020 – 2030
      • Market Size and Forecast (US$ Mn), By Country, 2020 – 2030
        • GCC
        • Israel
        • South Africa
        • Rest of Middle East
  9. Competitive Landscape
    • Heat Map Analysis
    • Market Presence and Specificity Analysis
  10. Company Profiles
      • Agilent Technologies, Inc. *
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
      • ATDBio Ltd.
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
      • Bio-Synthesis, Inc.
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
      • BioAutomation Corporation
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
      • LGC Biosearch Technologies
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
      • Biogen International
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
      • Sarepta Therapeutics
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
      • Eurofins Genomics
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
      • Eurogentec
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
      • GeneDesign, Inc.
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
      • GE Healthcare
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
      • GenScript, Inc.
        • Company Overview
        • Product Portfolio
        • Key Highlights
        • Financial Overview
  11. The Last Word
    • Future Impact
    • About Us
    • Contact

FAQs

The Global Oligonucleotide Synthesis Market is valued at US$5.12 billion in 2020

The Global Oligonucleotide Synthesis Market is projected to increase at a CAGR of 14.2% during the forecast period.

The global oligonucleotide synthesis market is segmented based product type, type, by application and region.

The oligonucleotide synthesis market is growing in continuously, because of growing government investments and R&D spending in pharmaceutical and biotechnology companies and the use of synthesized oligonucleotides in molecular diagnostics and clinical uses.

North America was the largest regional market for oligonucleotide synthesis in 2019

The key players in the market are focusing on increasing production with development of product.